Studies on Antiulcer Drugs. V. Synthesis and Antiulcer Activity of Aralkylbenzazoles.

Actions of antiulcer drugs.

Phenoxypropylamines: synthesis and antiulcer evaluation.

We have synthesized a number of phenoxypropylamines from N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}chloroacetamide (3). All the products have been characterized by elemental analysis, (1)H-NMR and MS. The biological activity effects of the title compounds were examined. From the biological activity results, we found that two of themshowed significant gastric acid antisecretory activity.

Antiulcer Activity of Pipal Extract

An ethanol extract of Pipal has been studied for its ability to inhibit gastric acidity and to protect gastric mucosa against the injuries caused by pyloric ligation, acetyl salicylic acid and cytodestructing agents (80% ethanol, 06M Hcl and 0.2 M Hcl) in rats. The results of this study demonstrate that ethanol extract of papal has significant effects on various experimentally induced ulcers. I...

ANTIULCER ACTIVITY OF AEGLE MARMELOS Linn

Aegle marmelos Linn is a common plant used to treat many disease Conditions in Indian traditional systems of medicine. The present study was undertaken to findout a scientific validation for the efficacy of Aegle marmelos against gastric ulcer. Aqueous extract of Aegle marmelos leaves was prepared and used for investigation. A daily does of 1 gm/kg body weight of the extract administered orally...

Synthesis and Antiulcer Activity Studies of 2-(1′-Iminothioimido Substituted)-1′-Substituted Phenylbenzoic acids

Certain 2-(1'-iminothioimido substituted)-1'-substituted phenybenzoic acids (P(1-9)) were synthesized by reaction of phthalic anhydride with benzotriazole, 2-mercapto benzothiazole and 2-p-amino phenyl benzimidazole, respectively (A(1-3)) followed by imine formation with Schiff bases of thiourea with salicylaldehyde, furfuraldehyde and 1-phenyl-3-methyl-5-pyrazolone. Antiulcer activity was eval...